Just as an experiment to see if it would, and YES I know the OS, Hardware and just about everything is "Not supported" but you can quite happily use iNotes Lite on a Intel P2 350MHz running Windows 98 SE in 192Mb of memory inside IE 6 SP1.
It takes about 15-20 secs to load the client post sign-on and between 3-5 seconds to load a 2000+ All Docs view.. and 3-5 secs to load a 3Mb message (no attachments but did have inline images)
So there you are... I wonder will it run on Win 95?